James McCullagh Selected Research

3'-deoxy-3',4'-didehydro-CTP

1/2020

ddhCTP produced by the radical-SAM activity of RSAD2 (viperin) inhibits the NAD+ -dependent activity of enzymes to modulate metabolism.

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James McCullagh Research Topics

Disease

5	Neoplasms (Cancer) 10/2021 - 09/2016
3	Type 2 Diabetes Mellitus (MODY) 12/2022 - 01/2019
3	Ovarian Neoplasms (Ovarian Cancer) 09/2021 - 09/2016
2	Inflammation (Inflammations) 12/2022 - 01/2019
2	Non-alcoholic Fatty Liver Disease 12/2022 - 02/2022
2	Virus Diseases (Viral Diseases) 01/2020 - 01/2020
1	COVID-19 11/2023
1	Obesity 12/2022
1	Hyperglycemia 11/2022
1	Insulin Resistance 02/2022
1	Overweight 02/2022
1	Body Weight (Weight, Body) 02/2022
1	Weight Loss (Weight Reduction) 02/2022
1	Breast Neoplasms (Breast Cancer) 10/2021
1	Triple Negative Breast Neoplasms 10/2021
1	Dehydration (Water Stress) 01/2020
1	Prostatic Neoplasms (Prostate Cancer) 01/2020
1	Neurodegenerative Diseases (Neurodegenerative Disease) 03/2019
1	Vascular Diseases (Vascular Disease) 01/2017
1	Phenylketonurias (Phenylketonuria) 01/2017
1	Cardiovascular Diseases (Cardiovascular Disease) 01/2017

Drug/Important Bio-Agent (IBA)

5	EnzymesIBA 01/2020 - 01/2017
2	NucleotidesIBA 10/2021 - 01/2020
2	Glucose (Dextrose)FDA LinkGeneric 10/2021 - 03/2019
2	lissamine rhodamine B (sulforhodamine B)IBA 09/2021 - 09/2016
2	S-Adenosylmethionine (Ademetionine)IBA 01/2020 - 01/2020
2	Antiviral Agents (Antivirals)IBA 01/2020 - 01/2020
2	AlkaloidsIBA 01/2018 - 09/2016
2	cycleanineIBA 01/2018 - 09/2016
1	VaccinesIBA 11/2023
1	OxylipinsIBA 12/2022
1	Unsaturated Fatty Acids (Polyunsaturated Fatty Acids)IBA 12/2022
1	PhosphofructokinasesIBA 11/2022
1	Insulin (Novolin)FDA Link 02/2022
1	IsotopesIBA 02/2022
1	Metformin (Glucophage)FDA LinkGeneric 02/2022
1	Triglycerides (Triacylglycerol)IBA 02/2022
1	Lactic Acid (Lactate)FDA LinkGeneric 10/2021
1	Estrogen ReceptorsIBA 10/2021
1	Progesterone Receptors (Progesterone Receptor)IBA 10/2021
1	Clerodane DiterpenesIBA 09/2021
1	Plant ExtractsIBA 09/2021
1	diphenyl (biphenyl)IBA 10/2020
1	BromidesIBA 10/2020
1	AntioxidantsIBA 10/2020
1	Proteins (Proteins, Gene)FDA Link 01/2020
1	AndrogensIBA 01/2020
1	ChromatinIBA 01/2020
1	3'-deoxy-3',4'-didehydro-CTPIBA 01/2020
1	G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA 11/2019
1	Butyrates (Butyrate)IBA 01/2019
1	ATP-Binding Cassette Transporters (ABC Transporters)IBA 01/2019
1	BenzylisoquinolinesIBA 01/2018
1	CaspasesIBA 01/2018
1	Superoxides (Superoxide)IBA 01/2017
1	GTP Cyclohydrolase (GTP Cyclohydrolase I)IBA 01/2017
1	Ethanol (Ethyl Alcohol)IBA 09/2016
1	tetrandrineIBA 09/2016

Therapy/Procedure

4	Therapeutics 10/2020 - 01/2017
2	Radiotherapy 10/2021 - 01/2020
1	Drug Therapy (Chemotherapy) 02/2022
1	Castration 01/2020